Collagen, a term you've likely encountered in the realms of skincare, joint health, or even overall wellness, is much more than just a buzzword. It’s a protein, and not just any protein – it's the most abundant one in the human body, accounting for about 30% of total protein content.[1] But what exactly is collagen, and why does it matter so much?
Collagen serves an essential role in maintaining the structure and integrity of our skin, bones, muscles, and even the gut. In fact, it’s the reason why our skin looks youthful and firm, and why our joints remain flexible as we move.
At its core, collagen acts as a building block that holds your body together. Without it, your skin would lose its elasticity, and joints could face wear and tear more easily.
Have you ever wondered why fine lines or joint discomfort become more apparent as we age? The answer lies in our body’s declining collagen production, which starts as early as our mid-20s.[2]
In this article, we’ll explore the science behind the best type of collagen and how supplementing it may benefit your health. By the end, you’ll have a clear understanding of collagen’s role in maintaining a healthy and vibrant body, and why it’s something worth paying attention to as you age.
What is Collagen?
Collagen is often described as the "scaffolding" of the human body. According to Wu, M., Cronin, K., & Crane, J. S., "Collagen is protein molecules made up of amino acids. It provides structural support to the extracellular space of connective tissues. Due to its rigidity and resistance to stretching, it is the perfect matrix for skin, tendons, bones, and ligaments."[3]
In simpler terms, collagen is like the glue that holds your body together. It provides strength and elasticity to your skin, cushions your joints, and supports the muscles and bones. Collagen fibers are incredibly strong and flexible, making them critical for a wide range of bodily functions.
Types of Collagen
Not all collagen is the same. In fact, there are over 28 different types of collagen, but the most abundant and important ones in the human body are Collagen Types I, II, and III.[3]
Types of Collagen
- Type I Collagen: This is the most prevalent type, making up around 90% of the collagen in the body. It is essential for maintaining the structure of skin, bones, and connective tissues. According to a study by Ricard-Blum, "Type I collagen is the major component of the extracellular matrix of skin, bones, and tendons".[4]
- Type II Collagen: Found mainly in cartilage, this type is crucial for joint health and flexibility. Research published in PMC shows that Type II collagen is "the primary collagen in cartilage and plays a significant role in joint function".[5]
- Type III Collagen: Often found alongside Type I, this collagen type supports the structure of organs like the liver and lungs and contributes to skin elasticity. A study published in PMC notes, "Type III collagen is essential for the normal functioning of hollow organs and maintaining the elasticity of tissues".[6]
How Does Collagen Production Decline with Age?
As we age, our body’s collagen production decreases, leading to visible signs of aging like wrinkles and joint stiffness. The Nebraska Methodist Health System states that "Collagen production declines by about 1% each year after the age of 20".[7]
This decline not only affects the skin's firmness and hydration but also impacts joint health and muscle mass, leading to stiffness and discomfort over time.
This gradual reduction in collagen is a natural part of the aging process, but factors such as sun exposure, smoking, and poor diet can accelerate this decline. Understanding how collagen works and declines with age helps explain why supplements and collagen-rich diets have gained popularity.
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Collagen’s Role in Skin Elasticity and Hydration
Collagen, the most abundant protein in the human body, plays a fundamental role in maintaining the structure, elasticity, and hydration of the skin. It constitutes approximately 80% of the skin’s dry weight, contributing to its firmness and resilience.[8]
The study titled "Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis” of 26 randomized controlled trials (RCTs), involving 1,721 participants, has demonstrated the significant impact of hydrolyzed collagen (HC) supplementation on improving skin hydration and elasticity.
The study found that oral collagen supplementation increased skin hydration and elasticity compared to placebo groups, with a 0.63 standard mean difference (SMD) for hydration and a 0.72 SMD for elasticity.[8] These improvements were particularly notable after 8 weeks or more of supplementation.[8]
How Do Collagen Supplements Reduce Wrinkles and Fine Lines?- Reduction in Wrinkles: Collagen supplements restore skin elasticity and reduce wrinkle depth, with studies showing a 38% improvement in skin elasticity after 12 weeks.[8]
- Improved Hydration: Collagen supports hyaluronic acid production, enhancing the skin's moisture retention.[8]
- Enhanced Texture: Collagen reduces trans-epidermal water loss, leading to smoother, more hydrated skin, with a 12.5% increase in skin hydration reported between 6 to 12 weeks of supplementation.[8]
Collagen's Role in Cartilage and Joint Structure
Collagen is the primary structural protein in cartilage and joint tissues, accounting for 80% of cartilage's dry weight.[9] It plays a critical role in providing tensile strength and maintaining the integrity of the joints.
To discover more facts about the benefits of collagen for joint health, we consulted with Dr. Ryan Peterson a board-certified physician specializing in anesthesiology and pain medicine said
Because collagen is the primary structural protein in cartilage, which cushions joints and promotes mobility, and structural support, collagen is essential for maintaining joint health. Collagen supplements can help relieve joint discomfort and increase flexibility, particularly for people with osteoarthritis or those who participate in high-impact sports.
The type II collagen, particularly abundant in cartilage, is essential for its function in joint health. In osteoarthritis (OA), the degradation of one of the best types of collagen leads to cartilage breakdown, joint stiffness, and pain. Collagen’s mechanical properties allow it to cushion joints and maintain joint flexibility.
How Do Collagen Supplements Help with Joint Pain?- Reduction in Joint Pain and Stiffness: Clinical trials show that type II collagen (40 mg/day) and hydrolyzed collagen (5-10 g/day) can significantly reduce joint pain and stiffness in osteoarthritis patients. After 6 months of hydrolyzed collagen supplementation, participants reported improved joint function and reduced discomfort as indicated by lower WOMAC pain scores.[9]
- Cartilage Regeneration: Hydrolyzed collagen stimulates cartilage synthesis, improving joint structure. A daily intake of 10 g of hydrolyzed collagen over 24 weeks increases proteoglycan content in knee cartilage, helping to slow cartilage degradation.[9]
- Inflammation Control: Type II collagen reduces inflammation by modulating the immune response. A study with 40 mg/day of type II collagen showed a significant reduction in inflammatory markers, preventing further cartilage destruction and alleviating pain in osteoarthritis patients.[9]
Collagen’s Role in Gut Health
Collagen supports the integrity of the intestinal lining by strengthening tight junctions (TJs), which regulate gut permeability. By reducing "leaky gut," collagen peptides prevent harmful substances from crossing the intestinal barrier, reducing inflammation and digestive issues.
The study titled "Effect of a Daily Collagen Peptide Supplement on Digestive Symptoms in Healthy Women: 2-Phase Mixed Methods Study" aimed to investigate the impact of collagen peptide supplementation on digestive health, focusing primarily on symptoms like bloating, constipation, and acid reflux.
The research involved an 8-week intervention where participants took 20 g of collagen peptides daily, and it showed a 93% reduction in digestive symptoms among those who completed the study, with significant improvements in bloating and bowel regularity.[10]
How Do Collagen Supplements Support Gut Health and Digestion?- Reduction in Gut Permeability: Collagen peptides restore the gut barrier, preventing conditions like irritable bowel syndrome (IBS) associated with increased gut permeability.[10]
- Alleviation of Digestive Symptoms: A study involving 20 g of daily collagen peptides over 8 weeks showed a 31% reduction in bloating and a 19% improvement in constipation symptoms. This, one of the best types of collagen helps improve gut barrier function and reduce inflammation.[10]
- Improved Bowel Regularity: Participants experienced better bowel regularity, moving from infrequent to daily bowel movements, likely due to collagen's role in promoting tissue repair in the digestive tract.[10]
Collagen’s Role in Muscle Tissue and Connective Tissue
Collagen is vital for the muscle's extracellular matrix (ECM), transmitting contractile forces to tendons and bones. Collagen fibers maintain tissue elasticity, playing a key role in muscle strength and function. During physical stress, such as exercise, collagen helps transmit force and supports muscle recovery.
The study titled "The Impact of Collagen Protein Ingestion on Musculoskeletal Connective Tissue Remodeling: A Narrative Review" investigates the role of collagen protein in supporting connective tissue remodeling and its effects on muscle tissue and connective tissue.[11]
Collagen is rich in proline and glycine, crucial amino acids for connective tissue synthesis. Unlike typical proteins like whey or casein, which lack sufficient levels of these amino acids, collagen supplementation provides the necessary precursors for effective connective tissue remodeling, making it an ideal support for muscle and tissue repair.
How Do Collagen Supplements Help in Muscle Recovery and Growth?- Enhanced Muscle Recovery: Collagen peptides provide essential amino acids like proline and glycine, which support connective tissue repair and improve muscle recovery after physical activity. This is vital for athletes and those engaged in resistance training.[11]
- Improvement in Muscle Growth and Strength: Studies show collagen supplementation enhances muscle mass and strength during resistance training. For example, a study on men with sarcopenia reported a 4.2 kg increase in fat-free mass with 15 g of collagen daily, compared to 2.9 kg in the placebo group.[11]
- Support for Connective Tissue Health: Collagen promotes tendon and ligament health, improving joint stability and flexibility, which reduces injury risk and supports overall muscle functionality.[11]
Side Effects of Collagen
Best collagen supplements are generally well-tolerated and have no major side effects:
Minor side effects: Some people may experience minor side effects like[12]
- a feeling of heaviness in your stomach
- mild diarrhoea
- rashes.
No adverse events: Some studies have found no adverse events or side effects in the treatment or control groups.[13]
While collagen supplements are generally considered safe for most individuals, there are a few important safety considerations to keep in mind. First, people with allergies to common collagen sources like fish, shellfish, or eggs should be cautious, as many collagen supplements are derived from these ingredients.
Additionally, individuals with pre-existing medical conditions, pregnant or breastfeeding women, and those on medications should consult with a healthcare provider before starting collagen supplementation to ensure it doesn’t interact with their health needs or current treatments.
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Dosage
The recommended dosage for collagen supplements varies depending on the form of collagen and the intended health benefits. It's best to follow the specific dosage instructions on the product or consult a healthcare professional for personalized recommendations.
Collagen Forms
Collagen supplements come in various forms, allowing individuals to choose the most convenient option for their lifestyle and preferences. Here are the most common forms:
- Collagen Powders: Collagen powder can be mixed into drinks such as water, smoothies, or coffee. It is typically tasteless and dissolves well, making it a convenient option for daily intake.
- Collagen Capsules or Pills: For those who prefer a more straightforward option, collagen capsules provide a pre-measured dose. This form is ideal for individuals who don't want to mix powder into drinks or deal with taste concerns.
- Collagen Liquids: These are pre-mixed collagen supplements in liquid form, often flavored, and are convenient for quick consumption.
- Collagen Gummies: These chewable supplements are a tastier option, often sweetened and flavored. While convenient and enjoyable, they may contain added sugars.
- Collagen-Infused Foods and Drinks: Some companies offer collagen-enhanced snacks, protein bars, and beverages, providing an easy way to integrate collagen into everyday meals.
Each form has its advantages, and choosing the right one depends on personal preferences, lifestyle, and how seamlessly you want to incorporate collagen into your routine.
Frequently Asked Questions
What is the benefit of taking collagen?
Taking collagen can improve skin elasticity, joint health, and muscle recovery.
What is the downside of taking collagen?
Some individuals may experience minor digestive discomfort or allergic reactions.
What exactly is in collagen?
Collagen is a protein composed of amino acids like glycine and proline, which are crucial for connective tissue.
What food is rich in collagen?
Foods rich in collagen include bone broth, chicken skin, and fish.
Is it OK to have collagen every day?
Yes, it's generally safe to consume collagen daily, but consult a healthcare provider for personalized advice.
What happens to your body when you start taking collagen?
Your body may experience improved skin hydration, reduced joint pain, and enhanced muscle function.
Can collagen supplements help with aging?
Yes, collagen can reduce fine lines and wrinkles by improving skin elasticity.
Are there any side effects of collagen supplements?
Side effects are rare but can include digestive discomfort and mild allergic reactions.
Can collagen improve digestive health?
Yes, collagen can enhance gut health by strengthening the intestinal lining and reducing symptoms like bloating.
Final Thoughts
Collagen supplements offer a range of benefits for skin, joint, gut, and muscle health. They can improve skin elasticity, hydration, and texture while reducing wrinkles and fine lines.
For joint health, collagen supports cartilage regeneration, reduces pain and stiffness, and controls inflammation. It also strengthens the gut barrier, alleviates digestive symptoms, and enhances muscle recovery and growth.
Despite the benefits, potential risks include minor side effects like digestive discomfort or allergic reactions in individuals sensitive to common collagen sources such as fish or eggs.
It’s essential to consult a healthcare professional before incorporating collagen supplements, especially for individuals with pre-existing conditions or dietary restrictions.
To incorporate collagen into a healthy lifestyle, it is recommended to choose high-quality supplements. Consistent use over several weeks may provide the best results.